50-State Healthcare and Pharmaceutical Licensing Compliance Guide
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South Carolina Healthcare and Pharmaceutical Licensing

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Licensing requirements for South Carolina healthcare and pharmaceutical companies and individuals.

This page provides an overview of healthcare and pharmaceutical industry licensing in South Carolina for individuals and businesses. You will find state requirements, application fees, filing instructions, and more. For assistance with licensing, please contact us to learn about our software and managed license services.

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Company Licenses

South Carolina Healthcare and Pharmaceutical Company Licenses

South Carolina Controlled Substances Registration - Animal Control/Shelter

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Controlled Substances Registration - Automated Storage Machine (ASM)

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Controlled Substances Registration - EMS/Rescue Squad

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Controlled Substances Registration - Health Clinic

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Controlled Substances Registration - Narcotic Treatment Program

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Controlled Substances Registration - Pharmacy

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina EMS Non-Dispensing Drug Outlet Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

EMS Non-Dispensing Drug Outlet Permit Application

Filing Method:

Mail

Agency Fee:

$280

Original Ink:Not required
Notarization Required?:Not required

Registration Renewal

Filing Method:

Online

Agency Fee:

$140

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Original Ink:Not required
Notarization Required?:Not required
Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

South Carolina Federally Qualified Health Center (FQHC) Drug Outlet Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Federally Qualified Health Center Drug (FQHC) Drug Outlet Application

Filing Method:

Mail

Agency Fee:

$280

Original Ink:Not required
Notarization Required?:Not required

Registration Renewal

Filing Method:

Online

Agency Fee:

$140

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Original Ink:Not required
Notarization Required?:Not required
Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

South Carolina Medical Gases/Legend Devices Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Medical Gases/Legend Device Permit Application

Filing Method:

Mail

Agency Fee:

$280

Registration Renewal

Filing Method:

Online

Agency Fee:

$140

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

South Carolina Non-Dispensing Drug Outlet Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Non-Dispensing Drug Outlet Permit Application

Filing Method:

Mail

Agency Fee:

$280

Registration Renewal

Filing Method:

Online

Agency Fee:

$140

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

South Carolina Non-Practitioner Controlled Substances Registration - Analytical/Forensic Lab

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Non-Practitioner Controlled Substances Registration - Canine Unit

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Non-Practitioner Controlled Substances Registration - Distributor

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Non-Practitioner Controlled Substances Registration - Exporter/Importer

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Non-Practitioner Controlled Substances Registration - Hospital

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Non-Practitioner Controlled Substances Registration - Importer/Exporter/Broker/Forwarder

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Non-Practitioner Controlled Substances Registration - Manufacturer

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Non-Resident Medical Gases/Legend Devices Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Non-Resident Medical Gas & Legend Device Permit Application

Filing Method:

Mail

Agency Fee:

$420

Registration Renewal

Filing Method:

Online

Agency Fee:

$280

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

Notes:

Applications are sent in the mail prior to expiration.

South Carolina Non-Resident Non-Dispensing Pharmacy Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Non-resident Non-dispensing Pharmacy Application

Filing Method:

Mail

Agency Fee:

$420

Registration Renewal

Filing Method:

Online

Agency Fee:

$280

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

Notes:

Applications are sent in the mail prior to expiration.

South Carolina Non-Resident Outsourcing Facility Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Non-Resident Outsourcing Facility Application

Filing Method:

Mail

Agency Fee:

$700

Registration Renewal

Filing Method:

Online

Agency Fee:

$700

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

Notes:

Applications are sent in the mail prior to expiration.

South Carolina Non-Resident Pharmacy Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Non-Resident Pharmacy Permit Application

Filing Method:

Mail

Agency Fee:

$420

Registration Renewal

Filing Method:

Online

Agency Fee:

$280

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

Notes:

Applications are sent in the mail prior to expiration.

South Carolina Non-Resident Third Party Logistics Provider Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Non-Resident Third Party Logistics Provider

Filing Method:

Mail

Agency Fee:

$700

Registration Renewal

Filing Method:

Online

Agency Fee:

$700

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

Notes:

Applications are sent in the mail prior to expiration.

South Carolina Non-Resident Wholesale/Distributor and/or Manufacturer Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Non Resident Wholesale Distributor and/or Manufacturer Application

Filing Method:

Mail

Agency Fee:

$700

Registration Renewal

Filing Method:

Online

Agency Fee:

$700

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

Notes:

Applications are sent in the mail prior to expiration.

South Carolina Outsourcing Facility Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Outsourcing Facility (503B) Permit Application

Filing Method:

Mail

Agency Fee:

$280

Registration Renewal

Filing Method:

Online

Agency Fee:

$140

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

South Carolina Pharmacy Permit

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy
Registered Agent (Special Agency) Required?No

Initial Registration

Form:

Pharmacy Permit Application

Filing Method:

Mail

Agency Fee:

$280

Registration Renewal

Filing Method:

Online

Agency Fee:

$140

Due:

Licenses expire annually on June 30. All renewal applications and fees must be submitted on or by May 31 to avoid late fees and penalties. 

Penalties:

$50 if not submitted by May 31. If not submitted by June 30, licenses will begin to incur an additional $10/day penalty and be considered lapsed. 

Individual Licenses

South Carolina Individual Healthcare and Pharmaceutical Licenses

South Carolina Controlled Substances Registration - Mid-Level Practitioner

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Controlled Substances Registration - Practitioner - DMD, DDS, DVM, or OD

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Controlled Substances Registration - Practitioner - MD or DO

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by October 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Non-Practitioner Controlled Substances Registration - Researcher

Agency:South Carolina Department of Health and Environmental Control - Bureau of Drug Control

Registration Renewal

Filing Method:

Online

Due:

Annually by April 1.

Notes:

Licensees are notified of the fee at the time of renewal.

South Carolina Pharmacist License

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Application by Exam

Filing Method:

Mail or online

Agency Fee:

$100

Notarization Required?:Required

Registration Renewal

Form:

Pharmacist Renewal Application

Filing Method:

Mail

Agency Fee:

$98

Due:

Licenses expire annually on April 30. Renewal applications must be postmarked on or before March 31 to avoid late fees and penalties. 

Penalties:
  • Renewals postmarked after April 1 will incur a penalty of $148
  • Renewal postmarked after May 1 will incur a penalty of $248
  • Renewals postmarked after May 16 will incur a penalty of $298
  • Renewals postmarked after June 1 will incur a penalty of $348
  • Renewals postmarked after June 16 will incur a penalty of $398
  • Licenses not renewed by July 1 will require a reinstatement application and may require a board appearance

South Carolina Pharmacy Intern Certificate

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

Pharmacy Intern Certificate Application

Filing Method:

Mail or online

Agency Fee:

$50

Notarization Required?:Required

Renewal Not Required

Not required



Intern certificates are valid for 6 years and cannot be renewed.

South Carolina Pharmacy Technician Registration

Agency:South Carolina Department of Labor Licensing and Regulation - Board of Pharmacy

Initial Registration

Form:

New Pharmacy Technician Registration Application

Filing Method:

Mail or online

Agency Fee:

$56

Notarization Required?:Required

Registration Renewal

Filing Method:

Online

Agency Fee:

$15

Due:

Annually by June 30.

Learn about healthcare and pharmaceutical licensing in other states:

Controlled Substance Registration - In addition to a pharmacy license, controlled substance registration registration is required in many states for pharmacies that distribute controlled substances.

NABP (National Association of Boards of Pharmacy) - Host a variety of programs and resources relating to pharmacist and pharmacy licensure and examination.

Pharmacist in Charge - A licensed pharmacist designated by a pharmacy to act as the party responsible for compliance with regulations.

VPP (Verified Pharmacy Program) - A program run by NABP that allows state boards to share information and more easily register out-of-state pharmacies.